This contribution develops a design of a closed system simulation loop for various modelling approaches in biomechanics. Two different modelling approaches are widely used describing anatomical joints which are based on different mathematical descriptions. Some basic insights to multibody models, based on ordinary differential equations and models based on partial differential equations are given. The fundamental distinctions between these two modelling approaches require different restrictions respectively reformulations. This work deals with finding requirements for both modelling approaches to achieve the incorporation into a closed feedback loop. The possibilities in the design of a closed feedback loop
depend on the simulation environments. The aim of this work is to establish a loop where as well the biomechanical model as the control tools are embedded in a powerful environment.