1. Proceedings
  2. I3M
  3. 2018
  4. SESDE
  5. 10.46354/i3m.2018.sesde.007

Modeling and simulation of blood flow and vessel stress in human brain during strenuous exercise

  • a Luhan Ma, 
  • b Ang Chen, 
  • c Yongbo Zhong, 
  • d Zhichao Ren, 
  • e Ye Lang, 
  • fJiazheng Zhao, 
  • gZhifeng Dong
  • abcdefgMechanical and Electronic Engineering Dept. of China University of Mining and Tech. (Beijing)
Cite as
Ma L., Chen A., Zhong Y., Ren Z., Lang Y., Zhao J., Dong Z. (2018). Modeling and simulation of blood flow and vessel stress in human brain during strenuous exercise. Proceedings of the 6th International Workshop on Simulation for Energy, Sustainable Development & Environment (SESDE 2018), pp. 40-46. DOI: https://doi.org/10.46354/i3m.2018.sesde.007

Abstract

In order to study the effect of strenuous exercise to human blood flow and vessels stress, the paper takes the central artery in human brain for an example, and carries out a two-way fluid-solid coupling finite element analysis on it. The three-dimensional model is reconstructed, and the calculation was made with Computational Fluid Dynamics software. The simulation results show that, a low velocity vortex region is formed in the sinus of the artery, and the vortex phenomenon is getting weaker with the increase of the acceleration value. The structure shape of blood vessel is the main factor affecting the wall shear stress and Mises stress. With the increase of the exercise acceleration, the maximum of wall shear stress and Mises stress of the vessel wall shows an approximate linear growth.

References

  1. Albert Y. C., Barry J. D., Jansen S., etc, 2017. Blood Flow Velocity Prediction in Aorto-iliac Stent Grafts Using Computational Fluid Dynamics and Taguchi Method. Computers in Biology and Medicine, 84, 235-246.
  2. William B., Miguel B., etc, 2016. Computational Fluid Dynamics Applied to the Study of Blood Flow in the Human Aortic Arch and its Main Branches. Ingenieria Investigacion y Tecnologia, 10, 45-60.
  3. Vergara C., Davide L. V., etc, 2017. Large eddy simulations of blood dynamics in abdominal aortic aneurysms. Medical Engineering and Physics, 000, 1-9.
  4. Cristian C. B., etc, 2017. Dynamic simulation and Doppler Ultrasonography validation of blood flow behavior in Abdominal Aortic Aneurysm, Physica Medica, 37, 1-8.
  5. Gerhard A. H., Ray W. O., 2010. Modelling the Layer-specific Three-dimensional Residual
    Stresses in Arteries, with an Application to the Human Aorta,23(7),787-799.
  6. Moore J. A., Steinman D. A., Holdsworth D. W., 1998. Accuracy of Computational Hemodunamics in Complex Arterial Geometries Reconstructed from Magnetic Resonance Imaging. Annals of Biomedical Engineering, 32(4), 104-117.
  7. Baumert M., Javorka M., etc, 2013. Joint symbolic analyses of heart rate, blood pressure, and respiratory dynamics. Journal of Electrocardiology, 46,569-573.
  8. Moreno-Quintanar G., Rivera W., Best R., 2012. Comparison of the experimental evaluation of a solar intermittent refrigeration system for ice production operating with the mixtures NH3-LiNO3 and NH3- LiNO3-H2O. Renewable Energy 38, 62-68.
  9. Liu Y., Zhang D. F., Bi Y. Q., Wang M. H., 2015. Analysis of Unstable Blood Flow in Aortic Arch and Branch Vessels. Applied Mathematics and Mechanics, 36(4), 432-438.
  10. Liu Z. M., Gao L. D., Shi L.，2013. Fluid-Solid Coupling Analysis of Coronary Artery bypass Graft Based on CT Imaging. Journal of Beijing University of Technology, 39(8), 1255-1260.