With the Industry 4.0 (I4.0) beginning, the world is witnessing an important technological development. The success of I4.0 is linked to the implementation of enabling technologies, including Machine Learning, which focuses on the machines’ ability to receive a series of data and learn on their own. The present research aims to systematically analyze the existing literature on the subject in various aspects, including publication year, authors, scientific sector, country, institution and keywords. Understanding and analyzing the existing literature on Machine Learning applied to predictive maintenance is preparatory to recommend policy on the subject.